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斯蒂芬•米勒

教授

生物化学

联系

  1. 电子邮件:smiller1@最佳线上娱乐swarthmore.edu
  2. 电话:(610)957 - 6063
  3. 办公室:科学中心288
  4. 实验室:科学中心289
斯蒂芬·米勒在他的实验室里和一群学生。

教育

他还是,Princeton University, 1992
博士,哈佛大学,1999年
路易斯·托马斯的家伙,普林斯顿大学,1999 - 2002
博士后,普林斯顿大学,2002 - 2004

课程

  • 化学10 h,荣誉普通化学研讨会
  • 普通化学化学10 h,荣誉
  • 化学,生物化学
  • 化学,生物化学
  • 化学58岁的高级生物化学实验
  • 108年化学,生物化学的主题

出版物(学生合作者下划线)

Torcato,贝聿铭Kasal,核磁共振布里托,由P.H.,Miller, S.T., Xavier, K.B. (2019) “Identification of novel AI-2 receptors in Clostridia reveals plasticity in the binding site of the LsrB receptor family.” J. Biol. Chem. 294 (12), 4450-4463.

品牌,j . C。,哦,即K。Ly, d . C。,Lamosa, P., Ventura, M. R., Miller, S. T., Xavier, K. B. (2014) “LsrF, a coenzyme A-dependent thiolase, catalyzes the terminal step in processing the quorum sensing signal autoinducer-2.” Proc. Natl. Acad. Sci. USA 111 (39), 14235–14240.

鲁伊·F。,品牌,j . C。,米勒,s T。,Maycock, C. D., Xavier, K. B., & Ventura, M.R. (2012) “Stereochemical diversity of AI-2 analogs modulates quorum sensing in Vibrio harveyi and Escherichia coli.” Bioorg. Med. Chem. 20 (1), 249-256.

Nicoludis, j·m·米勒,s T。,Jeffrey, P. Barrett, S. P, Rablen, P. R., Lawton, T., Yatsunyk, L. A. (2012) "Optimized end-stacking provides specificity of N-methyl mesoporphyrin IX for human telomeric G-quadruplex DNA" J. Am. Chem. Soc.134 (50), 20446-20456.

品牌,j . C。Lamosa, P。,Russell, C., Ventura, R., Maycock C., Semmelhack, M. F., Miller, S. T., and Xavier, K. B. (2011) "Processing the Interspecies Quorum-sensing Signal Autoinducer-2 (AI-2): Characterization of phospho-(S)-4,5-dihydroxy-2,3-pentanedione isomerization by LsrG protein." J. Biol. Chem. 287, 18331-18343.

米勒,s T。,Indivero, V. & Burkhard, C. (2009) “Expression and Purification of Sperm Whale Myoglobin.” J. Chem. Educ. In Press.

佩雷拉,c . S。,de Regt, A. K., Brito, P. H., Miller, S. T., & Xavier, K. B. (2009) “Identification of Functional LsrB-like Autoinducer-2 Receptors.” J. Bacteriol. doi:10.1128/JB.00976-09.

迪亚兹,Z。,Xavier, K. B. & Miller, S. T. (2009) “The Crystal Structure of the Escherichia coli Autoinducer-2 Processing Protein LsrF.” PLoS ONE. 4(8), e6820.

佩雷拉,C。,McAuley, J. R., Taga, M. E., Xavier, K. B., & Miller, S. T. (2008) “Sinorhizobium meliloti, a Bacterium Lacking the Autoinducer-2 (AI-2) Synthase, Responds to AI-2 Supplied by Other Bacteria.” Mol. Micro. 70, 1223-1235.

泽维尔,K.B.,Miller, S.T., Kim, JH, Lu, W., Rabinowitz. J., Pelczer, I., Semmelhack, M.F., Bassler, B. L. (2007) “Phosphorylation and Processing of the Quorum Sensing Molecule AI-2 in Enteric Bacteria.” ACS Chemical Biology. 2, 128-136.

Neiditch, M.B.,M.J. Federle, S.T. Miller, B.L. Bassler and F.M. Hughson. (2005) “Regulation of LuxPQ Receptor Activity by the Quorum-Sensing Signal Autoinducer-2.” Mol. Cell 18, 507-518.

米勒,s T。,K. Xavier, S. Campagna, M. Taga, M. F. Semmelhack, B. L. Bassler & F. M. Hughson. (2004) “The Salmonella typhimurium Recognizes a Chemically Distinct Form of the Bacterial Quorum-Sensing Signal AI-2.” Mol. Cell 15, 677-687.

Das, J。,S. T. Miller & D. L. Stern. (2004) “Comparison of Diverse Protein Sequences of the Nuclear-Encoded Subunits of Cytochrome C Oxidase Suggests Conservation of Structure Underlies Evolving Functional Sites.” Mol. Biol. and Evol. 21, 1572-1582.

Taga, M。,S. T. Miller & B. L. Bassler. (2003) “Lsr-Mediated Transport and Processing of AI-2 in Salmonella typhimurium.” Mol. Microbiol. 50, 1411-1427.

米勒,s T。,J。M. Hogle & D. J. Filman. (2001) “Ab initio Phasing of High-Symmetry Macromolecular Complexes: Successful Phasing of Authentic Poliovirus Data to 3.0Å Resolution.” J. Mol. Biol. 307, 499-512.

米勒,s T。,J。Genova & J. M. Hogle. (1999). “Collection of Very Low Resolution Protein Data.” J. Appl. Cryst. 32:1183-1185.

米勒,s T。,J。M. Hogle & D. J. Filman. (1996). “A Genetic Algorithm for the ab initio Phasing of Icosahedral Viruses.” Acta Crystallographica D52:235-251.

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